High Density Lipoprotein Protects Mesenchymal Stem Cells from Oxidative Stress-Induced Apoptosis via Activation of the PI3K/Akt Pathway and Suppression of Reactive Oxygen Species

High Density Lipoprotein Protects Mesenchymal Stem Cells from Oxidative Stress-Induced Apoptosis via Activation of the PI3K/Akt Pathway and Suppression of Reactive Oxygen Species

The therapeutic effect of transplantation of mesenchymal stem cells (MSCs) in myocardial infarction (MI) appears to be limited by poor cell viability in the injured tissue, which is a consequence of oxidative stress and pro-apoptotic factors. High density lipoprotein (HDL) reverses cholesterol trans...

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Bibliographic Details
Main Authors: Xu, Jianfeng, Qian, Juying, Xie, Xinxing, Lin, Li, Zou, Yunzeng, Fu, Mingqiang, Huang, Zheyong, Zhang, Guoping, Su, Yangang, Ge, Junbo
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546741/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546741/

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