1-Benzyl-2-Phenylbenzimidazole (BPB), a Benzimidazole Derivative, Induces Cell Apoptosis in Human Chondrosarcoma through Intrinsic and Extrinsic Pathways
In this study, we investigated the anticancer effects of a new benzimidazole derivative, 1-benzyl-2-phenyl -benzimidazole (BPB), in human chondrosarcoma cells. BPB-mediated apoptosis was assessed by the MTT assay and flow cytometry analysis. The in vivo efficacy was examined in a JJ012 xenograft mod...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International (MDPI)
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546702/ |