Form Follows Function: Structural and Catalytic Variation in the Class A Flavoprotein Monooxygenases
Flavoprotein monooxygenases (FPMOs) exhibit an array of mechanistic solutions to a common chemical objective; the monooxygenation of a target substrate. Each FPMO efficiently couples reduction of a flavin cofactor by NAD(P)H to oxygenation of the target substrate via a (hydro)peroxyflavin intermedia...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Molecular Diversity Preservation International (MDPI)
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546652/ |