Using an experimental medicine model to understand the antidepressant potential of the N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine
There is growing interest in the role of the glutamatergic system both in depression and as a novel target for treatments. Preclinical studies suggested that the non-competitive N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine might have antidepressant properties, but a randomised contr...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
SAGE Publications
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546643/ |