Genetic Variation in Plant CYP51s Confers Resistance against Voriconazole, a Novel Inhibitor of Brassinosteroid-Dependent Sterol Biosynthesis

Brassinosteroids (BRs) are plant steroid hormones with structural similarity to mammalian sex steroids and ecdysteroids from insects. The BRs are synthesized from sterols and are essential regulators of cell division, cell elongation and cell differentiation. In this work we show that voriconazole,...

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Bibliographic Details
Main Authors: Rozhon, Wilfried, Husar, Sigrid, Kalaivanan, Florian, Khan, Mamoona, Idlhammer, Markus, Shumilina, Daria, Lange, Theo, Hoffmann, Thomas, Schwab, Wilfried, Fujioka, Shozo, Poppenberger, Brigitte
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546049/