Disrupted erythropoietin signaling promotes obesity and alters hypothalamus proopiomelanocortin production

While erythropoietin is the cytokine known that regulates erythropoiesis, erythropoietin receptor (EpoR) expression and associated activity beyond hematopoietic tissue remain uncertain. Here we show that mice with EpoR expression restricted to hematopoietic tissues (Tg) develop obesity and insulin r...

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Bibliographic Details
Main Authors: Teng, Ruifeng, Gavrilova, Oksana, Suzuki, Norio, Chanturiya, Tatyana, Schimel, Daniel, Hugendubler, Lynne, Mammen, Selin, Yver, Dena R., Cushman, Samuel W., Mueller, Elisabetta, Yamamoto, Masayuki, Hsu, Lewis L., Noguchi, Constance Tom
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542973/