Neutralization of complement component C5 ameliorates the development of dextran sulfate sodium (DSS)-colitis in mice

The complement system is a potent effector of innate immunity. To elucidate the pathophysiological role of the complement system in inflammatory bowel disease, we evaluated the effects of anti-C5 antibodies on the development of dextran sulfate sodium-induced colitis in mice. Dextran sulfate sodium-...

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Bibliographic Details
Main Authors: Aomatsu, Tomoki, Imaeda, Hirotsugu, Takahashi, Kenichiro, Fujimoto, Takehide, Kasumi, Eiji, Ban, Hiromitsu, Bamba, Shigeki, Yoden, Atsushi, Tamai, Hiroshi, Fujiyama, Yoshihide, Andoh, Akira
Format: Online
Language:English
Published: the Society for Free Radical Research Japan 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541422/