IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates

IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates

The development of dyskinesias following chronic L-DOPA replacement therapy remains a major problem in the long-term treatment of Parkinson’s disease. This study aimed at evaluating the effect of IRC-082451 (base of BN82451), a novel multitargeting hybrid molecule, on L-DOPA-induced dyskinesias (LID...

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Bibliographic Details
Main Authors: Aron Badin, Romina, Spinnewyn, Brigitte, Gaillard, Marie-Claude, Jan, Caroline, Malgorn, Carole, Van Camp, Nadja, Dollé, Frédéric, Guillermier, Martine, Boulet, Sabrina, Bertrand, Anne, Savasta, Marc, Auguet, Michel, Brouillet, Emmanuel, Chabrier, Pierre-Etienne, Hantraye, Philippe
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536787/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536787/

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