A Comparative Approach to Understanding Tissue-Specific Expression of Uncoupling Protein 1 Expression in Adipose Tissue

The thermoregulatory function of brown adipose tissue (BAT) is due to the tissue-specific expression of uncoupling protein 1 (UCP1) which is thought to have evolved in early mammals. We report that a CpG island close to the UCP1 transcription start site is highly conserved in all 29 vertebrates exam...

Full description

Bibliographic Details
Main Authors: Shore, Andrew, Emes, Richard D., Wessely, Frank, Kemp, Paul, Cillo, Clemente, D’Armiento, Maria, Hoggard, Nigel, Lomax, Michael A.
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535714/