Protein refolding in peroxisomes is dependent upon an HSF1-regulated function

Post-heat shock refolding of luciferase requires chaperones. Expression of a dominant negative HSF1 mutant (dnHSF1), which among other effects depletes cells of HSF1-regulated chaperones, blocked post-heat shock refolding of luciferase targeted to the cytoplasm, nucleus, or peroxisomes, while refold...

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Bibliographic Details
Main Authors: Heldens, Lonneke, van Genesen, Siebe T., Hanssen, Lars L. P., Hageman, Jurre, Kampinga, Harm H., Lubsen, Nicolette H.
Format: Online
Language:English
Published: Springer Netherlands 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535170/