Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?

The differential diagnosis between idiopathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis(IPF)/usual interstitial pneumonia(UIP)is tough in both clinicians and pathologists. In this study, we analyzed the lesions of right lung removed from a 58-year-old patient by gro...

Full description

Bibliographic Details
Main Authors:	Fang, Xia, Luo, Benfang, Yi, Xianghua, Zeng, Yu, Liu, Fang, Li, Huiping, Gu, Pan, Zhu, Xuyou, Zhang, Suxia, Jiang, Gelin
Format:	Online
Language:	English
Published:	BioMed Central 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534605/

id	pubmed-3534605
recordtype	oai_dc
spelling	pubmed-35346052013-01-03 Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis? Fang, Xia Luo, Benfang Yi, Xianghua Zeng, Yu Liu, Fang Li, Huiping Gu, Pan Zhu, Xuyou Zhang, Suxia Jiang, Gelin Case Report The differential diagnosis between idiopathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis(IPF)/usual interstitial pneumonia(UIP)is tough in both clinicians and pathologists. In this study, we analyzed the lesions of right lung removed from a 58-year-old patient by gross and microscopy. The results showed that the pathological appearance of nonspecific interstitial pneumonia (NSIP) and UIP coexisted in his upper lobe. Besides, because of severe fibrosis in middle and lower lobes, it was hard to distinguish the lesions of NSIP fibrotic pattern (NSIP-F) or UIP. Based on clinic-radiologic-pathological data, the diagnosis of INSIP-F was made for this patient finally. Our study suggests that UIP is not always an accurate diagnosis when the NSIP and UIP coexist, and NSIP can have regions of UIP. BioMed Central 2012-12-03 /pmc/articles/PMC3534605/ /pubmed/23206520 http://dx.doi.org/10.1186/1746-1596-7-167 Text en Copyright ©2012 Fang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Fang, Xia Luo, Benfang Yi, Xianghua Zeng, Yu Liu, Fang Li, Huiping Gu, Pan Zhu, Xuyou Zhang, Suxia Jiang, Gelin
spellingShingle	Fang, Xia Luo, Benfang Yi, Xianghua Zeng, Yu Liu, Fang Li, Huiping Gu, Pan Zhu, Xuyou Zhang, Suxia Jiang, Gelin Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?
author_facet	Fang, Xia Luo, Benfang Yi, Xianghua Zeng, Yu Liu, Fang Li, Huiping Gu, Pan Zhu, Xuyou Zhang, Suxia Jiang, Gelin
author_sort	Fang, Xia
title	Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?
title_short	Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?
title_full	Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?
title_fullStr	Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?
title_full_unstemmed	Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?
title_sort	usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, what’s the diagnosis?
description	The differential diagnosis between idiopathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis(IPF)/usual interstitial pneumonia(UIP)is tough in both clinicians and pathologists. In this study, we analyzed the lesions of right lung removed from a 58-year-old patient by gross and microscopy. The results showed that the pathological appearance of nonspecific interstitial pneumonia (NSIP) and UIP coexisted in his upper lobe. Besides, because of severe fibrosis in middle and lower lobes, it was hard to distinguish the lesions of NSIP fibrotic pattern (NSIP-F) or UIP. Based on clinic-radiologic-pathological data, the diagnosis of INSIP-F was made for this patient finally. Our study suggests that UIP is not always an accurate diagnosis when the NSIP and UIP coexist, and NSIP can have regions of UIP.
publisher	BioMed Central
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534605/
_version_	1611944159603589120

Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?

Similar Items