Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc−/− Mice

Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc−/− Mice

Slow T-cell reconstitution is a major clinical concern after transplantation of cord blood (CB)-derived hematopoietic stem cells. Adoptive transfer of in vitro-generated T-cell progenitors has emerged as a promising strategy for promoting de novo thymopoiesis and thus accelerating T-cell reconstitut...

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Bibliographic Details
Main Authors: Reimann, Christian, Six, Emmanuelle, Dal-Cortivo, Liliane, Schiavo, Andrea, Appourchaux, Kevin, Lagresle-Peyrou, Chantal, de Chappedelaine, Corinne, Ternaux, Brigitte, Coulombel, Laure, Beldjord, Kheira, Cavazzana-Calvo, Marina, Andre-Schmutz, Isabelle
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531890/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531890/

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