Automated cleaning and pre-processing of immunoglobulin gene sequences from high-throughput sequencing
High-throughput sequencing (HTS) yields tens of thousands to millions of sequences that require a large amount of pre-processing work to clean various artifacts. Such cleaning cannot be performed manually. Existing programs are not suitable for immunoglobulin (Ig) genes, which are variable and often...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531709/ |