Central Nervous System Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in Young Children

Central Nervous System Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in Young Children

HIV-1 subtype B replication in the CNS can occur in CD4+ T cells or macrophages/microglia in adults. However, little is known about CNS infection in children or the ability of subtype C HIV-1 to evolve macrophage-tropic variants. In this study, we examined HIV-1 variants in ART-naïve children aged t...

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Bibliographic Details
Main Authors: Sturdevant, Christa Buckheit, Dow, Anna, Jabara, Cassandra B., Joseph, Sarah B., Schnell, Gretja, Takamune, Nobutoki, Mallewa, Macpherson, Heyderman, Robert S., Van Rie, Annelies, Swanstrom, Ronald
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531524/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531524/

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