SwissBioisostere: a database of molecular replacements for ligand design

The SwissBioisostere database (http://www.swissbioisostere.ch) contains information on molecular replacements and their performance in biochemical assays. It is meant to provide researchers in drug discovery projects with ideas for bioisosteric modifications of their current lead molecule, as well a...

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Bibliographic Details
Main Authors: Wirth, Matthias, Zoete, Vincent, Michielin, Olivier, Sauer, Wolfgang H. B.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531158/