Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells

Endoplasmic reticulum (ER) stress induces an mRNA decay pathway termed regulated Ire-dependent decay (RIDD). This study shows that in Drosophila cells, ER association is sufficient for targeting mRNAs to RIDD and most membrane-associated mRNAs are degraded more rapidly during ER stress. It is also r...

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Bibliographic Details
Main Authors: Gaddam, Deepika, Stevens, Nicole, Hollien, Julie
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530775/