Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota

Vaginal HIV microbicides offer great promise in preventing HIV transmission, but failures of phase 3 clinical trials, in which microbicide-treated subjects had an increased risk of HIV transmission, raised concerns about endpoints used to evaluate microbicide safety. A possible explanation for the i...

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Bibliographic Details
Main Authors: Ravel, Jacques, Gajer, Pawel, Fu, Li, Mauck, Christine K., Koenig, Sara S. K., Sakamoto, Joyce, Motsinger-Reif, Alison A., Doncel, Gustavo F., Zeichner, Steven L.
Format: Online
Language:English
Published: American Society of Microbiology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529542/