Resveratrol Prevents Ammonia Toxicity in Astroglial Cells

Ammonia is implicated as a neurotoxin in brain metabolic disorders associated with hyperammonemia. Acute ammonia toxicity can be mediated by an excitotoxic mechanism, oxidative stress and nitric oxide (NO) production. Astrocytes interact with neurons, providing metabolic support and protecting again...

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Bibliographic Details
Main Authors: Bobermin, Larissa Daniele, Quincozes-Santos, André, Guerra, Maria Cristina, Leite, Marina Concli, Souza, Diogo Onofre, Gonçalves, Carlos-Alberto, Gottfried, Carmem
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528750/