High-quality and high-avidity T cell clones specific for tumor-associated antigens and how to find them
The adoptive transfer of lymphocytes expressing high-avidity T-cell receptors with antitumor specificity provides a promising therapy for cancer patients. Recently, we compared 12 HLA-A2-restricted, tyrosinase peptide-specific CD8+ cytotoxic T-lymphocyte (CTL) clones and demonstrated that polyfuncti...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Landes Bioscience
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525631/ |