Surviving host innate immunity: Cancer cells can turn a deadly assault into an advantage

The entry of metastatic cancer cells into the liver can trigger a rapid inflammatory response with increased local production of tumor necrosis factor α (TNFα). We investigated the molecular mechanisms that protect tumor cells from TNFα-induced apoptosis. A molecular crosstalk between the TNFα/TNFR/...

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Bibliographic Details
Main Author: Brodt, Pnina
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525616/