HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity

DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal and dermal layers of the skin are characterized by an abundance of antigen-presenting cells (APCs)....

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Bibliographic Details
Main Authors: Nguyen-Hoai, Tam, Kobelt, Dennis, Hohn, Oliver, Vu, Minh D., Schlag, Peter M., Dörken, Bernd, Norley, Steven, Lipp, Martin, Walther, Wolfgang, Pezzutto, Antonio, Westermann, Jörg
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525609/