Comprehensive FISH Probe Design Tool Applied to Imaging Human Immunoglobulin Class Switch Recombination

We present a web engine boosted fluorescence in-situ hybridization (webFISH) algorithm using a genome-wide sequence similarity search to design target-specific single-copy and repetitive DNA FISH probes. The webFISH algorithm featuring a user-friendly interface (http://www.webfish2.org/) maximizes t...

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Bibliographic Details
Main Authors: Nedbal, Jakub, Hobson, Philip S., Fear, David J., Heintzmann, Rainer, Gould, Hannah J
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522715/