Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

Hypoxia is known to play critical roles in cell survival, angiogenesis, tumor invasion, and metastasis. Hypoxia mediated over-expression of hypoxia-inducible factor (HIF) has been shown to be associated with therapeutic resistance, and contributes to poor prognosis of cancer patients. Emerging evide...

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Bibliographic Details
Main Authors: Bao, Bin, Ali, Shadan, Ahmad, Aamir, Azmi, Asfar S., Li, Yiwei, Banerjee, Sanjeev, Kong, Dejuan, Sethi, Seema, Aboukameel, Amro, Padhye, Subhash B., Sarkar, Fazlul H.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521759/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521759/

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