SNAP-23 regulates phagosome formation and maturation in macrophages

SNAP-23 regulates phagosome formation and maturation in macrophages

Using macrophages overexpressing or reducing SNAP-23, this study shows that SNAP-23 is implicated in phagosome formation and maturation, presumably by mediating SNARE-based membrane traffic. Indeed, a conformational change in SNAP-23 structure based on FRET signal is observed on the phagosome membra...

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Bibliographic Details
Main Authors: Sakurai, Chiye, Hashimoto, Hitoshi, Nakanishi, Hideki, Arai, Seisuke, Wada, Yoh, Sun-Wada, Ge-Hong, Wada, Ikuo, Hatsuzawa, Kiyotaka
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521691/

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