Desensitization, Trafficking, and Resensitization of the Pituitary Thyrotropin-Releasing Hormone Receptor
The pituitary receptor for thyrotropin-releasing hormone (TRH) is a calcium-mobilizing G protein-coupled receptor (GPCR) that signals through Gq/11, elevating calcium, and activating protein kinase C. TRH receptor signaling is quickly desensitized as a consequence of receptor phosphorylation, arrest...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521152/ |