Cadherin-Mediated Cell Adhesion Is Critical for the Closing of the Mouse Optic Fissure

Coloboma is a congenital disease that contributes significantly to childhood blindness. It results from the failure in closing the optic fissure, a transient opening on the ventral side of the developing eye. Although human and mouse genetic studies have identified a number of genes associated with...

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Bibliographic Details
Main Authors: Chen, Shuyi, Lewis, Brandy, Moran, Andrea, Xie, Ting
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519883/