Antagonistic Pleiotropy and Fitness Trade-Offs Reveal Specialist and Generalist Traits in Strains of Canine Distemper Virus

Theoretically, homogeneous environments favor the evolution of specialists whereas heterogeneous environments favor generalists. Canine distemper is a multi-host carnivore disease caused by canine distemper virus (CDV). The described cell receptor of CDV is SLAM (CD150). Attachment of CDV hemaggluti...

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Bibliographic Details
Main Authors: Nikolin, Veljko M., Osterrieder, Klaus, von Messling, Veronika, Hofer, Heribert, Anderson, Danielle, Dubovi, Edward, Brunner, Edgar, East, Marion L.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519774/