A glypican-3-derived peptide vaccine against hepatocellular carcinoma

The results of a Phase I clinical trial in which a glypican-3 (GPC3)-derived peptide was tested in advanced hepatocellular carcinoma patients point to a strong correlation between immunological and clinical responses. This commentary reviews our fundamental studies and clinical trials on the GPC3-de...

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Bibliographic Details
Main Authors: Sawada, Yu, Sakai, Mayuko, Yoshikawa, Toshiaki, Ofuji, Kazuya, Nakatsura, Tetsuya
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518534/