NF90 coordinately represses the senescence-associated secretory phenotype

A hallmark trait of cellular senescence is the acquisition of a senescence-associated secretory phenotype (SASP). SASP factors include cytokines and their receptors (IL-6, IL-8, osteoprotegerin, GM-CSF), chemokines and their ligands (MCP-1, HCC4), and oncogenes (Gro1 and Gro2), many of them encoded...

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Bibliographic Details
Main Authors: Tominaga-Yamanaka, Kumiko, Abdelmohsen, Kotb, Martindale, Jennifer L., Yang, Xiaoling, Taub, Dennis D., Gorospe, Myriam
Format: Online
Language:English
Published: Impact Journals LLC 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517940/