Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

Meta-analyses of European populations has successfully identified genetic variants in over 100 loci associated with lipid levels, but our knowledge in other ethnicities remains limited. To address this, we performed dense genotyping of ∼2,000 candidate genes in 7,657 African Americans, 1,315 Hispani...

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Main Authors: Elbers, Clara C., Guo, Yiran, Tragante, Vinicius, van Iperen, Erik P. A., Lanktree, Matthew B., Castillo, Berta Almoguera, Chen, Fang, Yanek, Lisa R., Wojczynski, Mary K., Li, Yun R., Ferwerda, Bart, Ballantyne, Christie M., Buxbaum, Sarah G., Chen, Yii-Der Ida, Chen, Wei-Min, Cupples, L. Adrienne, Cushman, Mary, Duan, Yanan, Duggan, David, Evans, Michele K., Fernandes, Jyotika K., Fornage, Myriam, Garcia, Melissa, Garvey, W. Timothy, Glazer, Nicole, Gomez, Felicia, Harris, Tamara B., Halder, Indrani, Howard, Virginia J., Keller, Margaux F., Kamboh, M. Ilyas, Kooperberg, Charles, Kritchevsky, Stephen B., LaCroix, Andrea, Liu, Kiang, Liu, Yongmei, Musunuru, Kiran, Newman, Anne B., Onland-Moret, N. Charlotte, Ordovas, Jose, Peter, Inga, Post, Wendy, Redline, Susan, Reis, Steven E., Saxena, Richa, Schreiner, Pamela J., Volcik, Kelly A., Wang, Xingbin, Yusuf, Salim, Zonderland, Alan B., Anand, Sonia S., Becker, Diane M., Psaty, Bruce, Rader, Daniel J., Reiner, Alex P., Rich, Stephen S., Rotter, Jerome I., Sale, Michèle M., Tsai, Michael Y., Borecki, Ingrid B., Hegele, Robert A., Kathiresan, Sekar, Nalls, Michael A., Taylor, Herman A., Hakonarson, Hakon, Sivapalaratnam, Suthesh, Asselbergs, Folkert W., Drenos, Fotios, Wilson, James G., Keating, Brendan J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517599/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517599/

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