Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium
Microarray profiling of gene expression is widely applied in molecular biology and functional genomics. Experimental and technical variations make meta-analysis of different studies challenging. In a total of 3358 samples, all from German population-based cohorts, we investigated the effect of data...
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| Format: | Online |
| Language: | English |
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Public Library of Science
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517598/ |
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pubmed-3517598 |
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oai_dc |
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pubmed-35175982012-12-12 Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium Schurmann, Claudia Heim, Katharina Schillert, Arne Blankenberg, Stefan Carstensen, Maren Dörr, Marcus Endlich, Karlhans Felix, Stephan B. Gieger, Christian Grallert, Harald Herder, Christian Hoffmann, Wolfgang Homuth, Georg Illig, Thomas Kruppa, Jochen Meitinger, Thomas Müller, Christian Nauck, Matthias Peters, Annette Rettig, Rainer Roden, Michael Strauch, Konstantin Völker, Uwe Völzke, Henry Wahl, Simone Wallaschofski, Henri Wild, Philipp S. Zeller, Tanja Teumer, Alexander Prokisch, Holger Ziegler, Andreas Research Article Microarray profiling of gene expression is widely applied in molecular biology and functional genomics. Experimental and technical variations make meta-analysis of different studies challenging. In a total of 3358 samples, all from German population-based cohorts, we investigated the effect of data preprocessing and the variability due to sample processing in whole blood cell and blood monocyte gene expression data, measured on the Illumina HumanHT-12 v3 BeadChip array. Public Library of Science 2012-12-07 /pmc/articles/PMC3517598/ /pubmed/23236413 http://dx.doi.org/10.1371/journal.pone.0050938 Text en © 2012 Schurmann et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Schurmann, Claudia Heim, Katharina Schillert, Arne Blankenberg, Stefan Carstensen, Maren Dörr, Marcus Endlich, Karlhans Felix, Stephan B. Gieger, Christian Grallert, Harald Herder, Christian Hoffmann, Wolfgang Homuth, Georg Illig, Thomas Kruppa, Jochen Meitinger, Thomas Müller, Christian Nauck, Matthias Peters, Annette Rettig, Rainer Roden, Michael Strauch, Konstantin Völker, Uwe Völzke, Henry Wahl, Simone Wallaschofski, Henri Wild, Philipp S. Zeller, Tanja Teumer, Alexander Prokisch, Holger Ziegler, Andreas |
| spellingShingle |
Schurmann, Claudia Heim, Katharina Schillert, Arne Blankenberg, Stefan Carstensen, Maren Dörr, Marcus Endlich, Karlhans Felix, Stephan B. Gieger, Christian Grallert, Harald Herder, Christian Hoffmann, Wolfgang Homuth, Georg Illig, Thomas Kruppa, Jochen Meitinger, Thomas Müller, Christian Nauck, Matthias Peters, Annette Rettig, Rainer Roden, Michael Strauch, Konstantin Völker, Uwe Völzke, Henry Wahl, Simone Wallaschofski, Henri Wild, Philipp S. Zeller, Tanja Teumer, Alexander Prokisch, Holger Ziegler, Andreas Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium |
| author_facet |
Schurmann, Claudia Heim, Katharina Schillert, Arne Blankenberg, Stefan Carstensen, Maren Dörr, Marcus Endlich, Karlhans Felix, Stephan B. Gieger, Christian Grallert, Harald Herder, Christian Hoffmann, Wolfgang Homuth, Georg Illig, Thomas Kruppa, Jochen Meitinger, Thomas Müller, Christian Nauck, Matthias Peters, Annette Rettig, Rainer Roden, Michael Strauch, Konstantin Völker, Uwe Völzke, Henry Wahl, Simone Wallaschofski, Henri Wild, Philipp S. Zeller, Tanja Teumer, Alexander Prokisch, Holger Ziegler, Andreas |
| author_sort |
Schurmann, Claudia |
| title |
Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium |
| title_short |
Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium |
| title_full |
Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium |
| title_fullStr |
Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium |
| title_full_unstemmed |
Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium |
| title_sort |
analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium |
| description |
Microarray profiling of gene expression is widely applied in molecular biology and functional genomics. Experimental and technical variations make meta-analysis of different studies challenging. In a total of 3358 samples, all from German population-based cohorts, we investigated the effect of data preprocessing and the variability due to sample processing in whole blood cell and blood monocyte gene expression data, measured on the Illumina HumanHT-12 v3 BeadChip array. |
| publisher |
Public Library of Science |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517598/ |
| _version_ |
1611939021474234368 |