Neurodegenerative Evidence in Mice Brains with Cecal Ligation and Puncture-Induced Sepsis: Preventive Effect of the Free Radical Scavenger Edaravone

Sepsis is a major clinical challenge and septic encephalopathy is its nasty complication. The pathogenesis and underlying mechanisms of septic encephalopathy are not well understood. This study sought to fully characterize sepsis-associated biochemical and histopathological changes in brains of mice...

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Bibliographic Details
Main Authors: Yokoo, Hiroki, Chiba, Seiichi, Tomita, Kengo, Takashina, Michinori, Sagara, Hiroshi, Yagisita, Saburo, Takano, Yasuo, Hattori, Yuichi
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517559/