Attenuated Salmonella Typhimurium Lacking the Pathogenicity Island-2 Type 3 Secretion System Grow to High Bacterial Numbers inside Phagocytes in Mice

Attenuated Salmonella Typhimurium Lacking the Pathogenicity Island-2 Type 3 Secretion System Grow to High Bacterial Numbers inside Phagocytes in Mice

Intracellular replication within specialized vacuoles and cell-to-cell spread in the tissue are essential for the virulence of Salmonella enterica. By observing infection dynamics at the single-cell level in vivo, we have discovered that the Salmonella pathogenicity island 2 (SPI-2) type 3 secretory...

Full description

Bibliographic Details
Main Authors: Grant, Andrew J., Morgan, Fiona J. E., McKinley, Trevelyan J., Foster, Gemma L., Maskell, Duncan J., Mastroeni, Pietro
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516571/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516571/

Similar Items