Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr −/− Mice Compared to Nondiabetic LDLr −/− Mice

Background. Diabetes is associated with increased cardiovascular disease, but the underlying cellular and molecular mechanisms are poorly understood. One proposed mechanism is that diabetes aggravates atherosclerosis by enhancing plaque inflammation. The Akita mouse has recently been adopted as a r...

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Bibliographic Details
Main Authors: Engelbertsen, Daniel, To, Fong, Dunér, Pontus, Kotova, Olga, Söderberg, Ingrid, Alm, Ragnar, Gomez, Maria F., Nilsson, Jan, Bengtsson, Eva
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515907/