Variance in Epistasis Links Gene Regulation and Evolutionary Rate in the Yeast Genetic Interaction Network

Organisms face a constantly shifting landscape of environmental conditions and internal physiological states. How gene regulation and cellular functions are maintained across genetic and environmental variation is therefore a fundamental question in biology. Here, we analyze the Saccharomyces cerevi...

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Bibliographic Details
Main Authors: Fierst, Janna L., Phillips, Patrick C.
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514962/