Pomegranate Protection against Cardiovascular Diseases
The current paper summarizes the antioxidative and antiatherogenic effects of pomegranate polyphenols on serum lipoproteins and on arterial macrophages (two major components of the atherosclerotic lesion), using both in vitro and in vivo humans and mice models. Pomegranate juice and its by-products...
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| Format: | Online |
| Language: | English |
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Hindawi Publishing Corporation
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514854/ |
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pubmed-3514854 |
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pubmed-35148542012-12-14 Pomegranate Protection against Cardiovascular Diseases Aviram, Michael Rosenblat, Mira Review Article The current paper summarizes the antioxidative and antiatherogenic effects of pomegranate polyphenols on serum lipoproteins and on arterial macrophages (two major components of the atherosclerotic lesion), using both in vitro and in vivo humans and mice models. Pomegranate juice and its by-products substantially reduced macrophage cholesterol and oxidized lipids accumulation, and foam cell formation (the hallmark of early atherogenesis), leading to attenuation of atherosclerosis development, and its consequent cardiovascular events. Hindawi Publishing Corporation 2012 2012-11-18 /pmc/articles/PMC3514854/ /pubmed/23243442 http://dx.doi.org/10.1155/2012/382763 Text en Copyright © 2012 M. Aviram and M. Rosenblat. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Aviram, Michael Rosenblat, Mira |
| spellingShingle |
Aviram, Michael Rosenblat, Mira Pomegranate Protection against Cardiovascular Diseases |
| author_facet |
Aviram, Michael Rosenblat, Mira |
| author_sort |
Aviram, Michael |
| title |
Pomegranate Protection against Cardiovascular Diseases |
| title_short |
Pomegranate Protection against Cardiovascular Diseases |
| title_full |
Pomegranate Protection against Cardiovascular Diseases |
| title_fullStr |
Pomegranate Protection against Cardiovascular Diseases |
| title_full_unstemmed |
Pomegranate Protection against Cardiovascular Diseases |
| title_sort |
pomegranate protection against cardiovascular diseases |
| description |
The current paper summarizes the antioxidative and antiatherogenic effects of pomegranate polyphenols on serum lipoproteins and on arterial macrophages (two major components of the atherosclerotic lesion), using both in vitro and in vivo humans and mice models. Pomegranate juice and its by-products substantially reduced macrophage cholesterol and oxidized lipids accumulation, and foam cell formation (the hallmark of early atherogenesis), leading to attenuation of atherosclerosis development, and its consequent cardiovascular events. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514854/ |
| _version_ |
1611938194590269440 |