Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants

Background. Mucosal or oral tolerance, an established method for inducing low-risk antigen-specific hyporesponsiveness, has not been investigated in vascularized composite allograft (VCA) research. We studied its effects on recipient immune responses and VCA rejection. Methods. Lewis rats (n = 12;...

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Bibliographic Details
Main Authors: Wallace, Christopher Glenn, Yen, Chia-Hung, Yang, Hsiang-Chen, Lin, Chun-Yen, Wu, Ren-Chin, Huang, Wei-Chao, Lin, Jeng-Yee, Wei, Fu-Chan
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514848/