The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

Invading C. albicans hyphae are recognized by macrophages, activate the caspase-1/IL-1β pathway, and lead to the activation of IL-17 pathway to control the C. albicans infection.

Bibliographic Details
Main Authors: Cheng, Shih-Chin, van de Veerdonk, Frank L., Lenardon, Megan, Stoffels, Monique, Plantinga, Theo, Smeekens, Sanne, Rizzetto, Lisa, Mukaremera, Liliane, Preechasuth, Kanya, Cavalieri, Duccio, Kanneganti, Thirumala Devi, van der Meer, Jos W. M., Kullberg, Bart Jan, Joosten, Leo A. B., Gow, Neil A. R., Netea, Mihai G.
Format: Online
Language:English
Published: Society for Leukocyte Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513931/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513931/

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