Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups

A series of small synthetic arginine and tryptophan containing peptides was prepared and analyzed for their antibacterial activity. The effect of N-terminal substitution with metallocenoyl groups such as ferrocene (FcCO) and ruthenocene (RcCO) was investigated. Antibacterial activity in different me...

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Bibliographic Details
Main Authors: Albada, H Bauke, Chiriac, Alina-Iulia, Wenzel, Michaela, Penkova, Maya, Bandow, Julia E, Sahl, Hans-Georg, Metzler-Nolte, Nils
Format: Online
Language:English
Published: Beilstein-Institut 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511009/