RecA filament sliding on DNA facilitates homology search

During homologous recombination, RecA forms a helical filament on a single stranded (ss) DNA that searches for a homologous double stranded (ds) DNA and catalyzes the exchange of complementary base pairs to form a new heteroduplex. Using single molecule fluorescence imaging tools with high spatiotem...

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Bibliographic Details
Main Authors: Ragunathan, Kaushik, Liu, Cheng, Ha, Taekjip
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510455/