NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate
Embryonic Stem (ES) cells are able to give rise to the three germ layers of the embryo but are prevented from contributing to the trophoblast. The molecular nature of this barrier between embryonic and trophectodermal cell fates is not clear, but is known to involve DNA methylation. Here we demonstr...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509455/ |