Targeting developmental regulators of zebrafish exocrine pancreas as a therapeutic approach in human pancreatic cancer
Histone deacetylases (HDACs) and RNA polymerase III (POLR3) play vital roles in fundamental cellular processes, and deregulation of these enzymes has been implicated in malignant transformation. Hdacs and Polr3 are required for exocrine pancreatic epithelial proliferation during morphogenesis in zeb...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509454/ |