KRAS Mutation Is a Predictor of Oxaliplatin Sensitivity in Colon Cancer Cells

Molecular biomarkers to determine the effectiveness of targeted therapies in cancer treatment have been widely adopted in colorectal cancer (CRC), but those to predict chemotherapy sensitivity remain poorly defined. We tested our hypothesis that KRAS mutation may be a predictor of oxaliplatin sensit...

Full description

Bibliographic Details
Main Authors: Lin, Yu-Lin, Liau, Jau-Yu, Yu, Shan-Chi, Ou, Da-Liang, Lin, Liang-In, Tseng, Li-Hui, Chang, Yih-Leong, Yeh, Kun-Huei, Cheng, Ann-Lii
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508995/