Astrocyte TNFR2 is required for CXCL12-mediated regulation of oligodendrocyte progenitor proliferation and differentiation within the adult CNS

Multiple sclerosis (MS) is characterized by episodes of inflammatory demyelination with progressive failure of remyelination. Prior studies using murine models of MS indicate that remyelination within the adult central nervous system (CNS) requires the expression and activity of TNFR2 and CXCR4 by o...

Full description

Bibliographic Details
Main Authors: Patel, Jigisha R., Williams, Jessica L., Muccigrosso, Megan M., Liu, Laindy, Sun, Tao, Rubin, Joshua B., Klein, Robyn S.
Format: Online
Language:English
Published: Springer-Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508279/