Phase-contrast X-ray microtomography of mouse fetus
A phase-contrast X-ray microtomography system using the Talbot imaging has been built at the SPring-8 synchrotron radiation facility. This system has much higher density resolution than absorption-based X-ray microtomography. The tomographic sections of formalin-fixed mouse fetuses obtained with thi...
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The Company of Biologists
2012
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pubmed-35072842012-12-04 Phase-contrast X-ray microtomography of mouse fetus Hoshino, Masato Uesugi, Kentaro Yagi, Naoto Research Article A phase-contrast X-ray microtomography system using the Talbot imaging has been built at the SPring-8 synchrotron radiation facility. This system has much higher density resolution than absorption-based X-ray microtomography. The tomographic sections of formalin-fixed mouse fetuses obtained with this method clearly depict various organs without any staining at a pixel resolution of up to 5 µm. Since this technique allows us to obtain three-dimensional structural information without sectioning, it will be particularly useful to examine anomalies that take place during development. It can be also used to quantitatively measure volume and mass of organs during development. The Company of Biologists 2012-02-10 /pmc/articles/PMC3507284/ /pubmed/23213417 http://dx.doi.org/10.1242/bio.2012430 Text en © 2012. Published by The Company of Biologists Ltd http://creativecommons.org/licenses/by-nc-sa/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0/). |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Hoshino, Masato Uesugi, Kentaro Yagi, Naoto |
spellingShingle |
Hoshino, Masato Uesugi, Kentaro Yagi, Naoto Phase-contrast X-ray microtomography of mouse fetus |
author_facet |
Hoshino, Masato Uesugi, Kentaro Yagi, Naoto |
author_sort |
Hoshino, Masato |
title |
Phase-contrast X-ray microtomography of mouse fetus |
title_short |
Phase-contrast X-ray microtomography of mouse fetus |
title_full |
Phase-contrast X-ray microtomography of mouse fetus |
title_fullStr |
Phase-contrast X-ray microtomography of mouse fetus |
title_full_unstemmed |
Phase-contrast X-ray microtomography of mouse fetus |
title_sort |
phase-contrast x-ray microtomography of mouse fetus |
description |
A phase-contrast X-ray microtomography system using the Talbot imaging has been built at the SPring-8 synchrotron radiation facility. This system has much higher density resolution than absorption-based X-ray microtomography. The tomographic sections of formalin-fixed mouse fetuses obtained with this method clearly depict various organs without any staining at a pixel resolution of up to 5 µm. Since this technique allows us to obtain three-dimensional structural information without sectioning, it will be particularly useful to examine anomalies that take place during development. It can be also used to quantitatively measure volume and mass of organs during development. |
publisher |
The Company of Biologists |
publishDate |
2012 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507284/ |
_version_ |
1611935698889211904 |