The interrelationship between APC/C and Plk1 activities in centriole disengagement
Mother–daughter centriole disengagement, the necessary first step in centriole duplication, involves Plk1 activity in early mitosis and separase activity after APC/C activity mediates securin degradation. Plk1 activity is thought to be essential and sufficient for centriole disengagement with separa...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507193/ |