Centrosomal Localization of the Psoriasis Candidate Gene Product, CCHCR1, Supports a Role in Cytoskeletal Organization

CCHCR1 (Coiled-Coil α-Helical Rod protein 1), within the major psoriasis susceptibility locus PSORS1, is a plausible candidate gene with the psoriasis associated risk allele CCHCR1*WWCC. Although its expression pattern in psoriatic skin differs from healthy skin and its overexpression influences ce...

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Bibliographic Details
Main Authors: Tervaniemi, Mari H., Siitonen, H. Annika, Söderhäll, Cilla, Minhas, Gurinder, Vuola, Jyrki, Tiala, Inkeri, Sormunen, Raija, Samuelsson, Lena, Suomela, Sari, Kere, Juha, Elomaa, Outi
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506594/