STAT1-Regulated Lung MDSC-like Cells Produce IL-10 and Efferocytose Apoptotic Neutrophils With Relevance In Resolution of Bacterial Pneumonia

Bacterial pneumonia remains a significant burden worldwide. Although an inflammatory response in the lung is required to fight the causative agent, persistent tissue-resident neutrophils in non-resolving pneumonia can induce collateral tissue damage and precipitate acute lung injury. However, little...

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Bibliographic Details
Main Authors: Poe, Stephanie L., Arora, Meenakshi, Oriss, Timothy B., Yarlagadda, Manohar, Isse, Kumiko, Khare, Anupriya, Levy, David E., Lee, Janet S., Mallampalli, Rama, Ray, Anuradha, Ray, Prabir
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505806/