Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome

Polyarteritis nodosa (PAN) belongs to a group of necrotic angiitis. During the illness, necrotic changes are found in small and middle dimensions arteries. Primary Sjögren’s syndrome is a chronic, autoimmunological systematic illness of connective tissue with characteristic infiltration of lymphocyt...

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Main Authors:	Prajs, Krzysztof, Bobrowska-Snarska, Danuta, Skała, Magdalena, Brzosko, Marek
Format:	Online
Language:	English
Published:	Springer-Verlag 2010
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505537/

id	pubmed-3505537
recordtype	oai_dc
spelling	pubmed-35055372012-11-28 Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome Prajs, Krzysztof Bobrowska-Snarska, Danuta Skała, Magdalena Brzosko, Marek Case Report Polyarteritis nodosa (PAN) belongs to a group of necrotic angiitis. During the illness, necrotic changes are found in small and middle dimensions arteries. Primary Sjögren’s syndrome is a chronic, autoimmunological systematic illness of connective tissue with characteristic infiltration of lymphocytes and plasmatic cells in endocrine glands. Despite the fact that both disease entities are well known and primary Sjögren’s syndrome is the second most commonly appearing autoimmunological sickness, the coexistence of both simultaneously is described very rarely. So far only three such cases have been presented. The case of 53-year-old woman is presented, who since 2003 has been hospitalized due to her ailments several times, at surgery, internal medicine, and rheumatology wards. In 2006, she was admitted to rheumatology clinic of Pomeranian Medical University (PAM) to be diagnosed both subjectively and objectively. Additional examinations proved that she had been suffering from overlapping PAN and primary Sjögren’s syndrome (PSS). She fulfilled 5 out of 10 criteria for PAN and all criteria for PSS. For treatment the boluses of methyloprednisolon and cyclophosphamid every 4 weeks were used what resulted in curing the patient. Springer-Verlag 2010-05-18 2012-12 /pmc/articles/PMC3505537/ /pubmed/20480165 http://dx.doi.org/10.1007/s00296-010-1515-1 Text en © The Author(s) 2010
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Prajs, Krzysztof Bobrowska-Snarska, Danuta Skała, Magdalena Brzosko, Marek
spellingShingle	Prajs, Krzysztof Bobrowska-Snarska, Danuta Skała, Magdalena Brzosko, Marek Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome
author_facet	Prajs, Krzysztof Bobrowska-Snarska, Danuta Skała, Magdalena Brzosko, Marek
author_sort	Prajs, Krzysztof
title	Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome
title_short	Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome
title_full	Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome
title_fullStr	Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome
title_full_unstemmed	Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome
title_sort	polyarteritis nodosa and sjögren’s syndrome: overlap syndrome
description	Polyarteritis nodosa (PAN) belongs to a group of necrotic angiitis. During the illness, necrotic changes are found in small and middle dimensions arteries. Primary Sjögren’s syndrome is a chronic, autoimmunological systematic illness of connective tissue with characteristic infiltration of lymphocytes and plasmatic cells in endocrine glands. Despite the fact that both disease entities are well known and primary Sjögren’s syndrome is the second most commonly appearing autoimmunological sickness, the coexistence of both simultaneously is described very rarely. So far only three such cases have been presented. The case of 53-year-old woman is presented, who since 2003 has been hospitalized due to her ailments several times, at surgery, internal medicine, and rheumatology wards. In 2006, she was admitted to rheumatology clinic of Pomeranian Medical University (PAM) to be diagnosed both subjectively and objectively. Additional examinations proved that she had been suffering from overlapping PAN and primary Sjögren’s syndrome (PSS). She fulfilled 5 out of 10 criteria for PAN and all criteria for PSS. For treatment the boluses of methyloprednisolon and cyclophosphamid every 4 weeks were used what resulted in curing the patient.
publisher	Springer-Verlag
publishDate	2010
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505537/
_version_	1611935045552963584

Polyarteritis nodosa and Sjögren’s syndrome: overlap syndrome

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