Resilience of Norovirus GII.4 to Freezing and Thawing: Implications for Virus Infectivity

Genogroup II.4 norovirus (NoV) remains the predominant NoV strain in food- and water-borne outbreaks. Capsid integrity as well as viral RNA persistence were determined for GII.4 NoV by real-time RT-PCR after 1–14 freeze/thaw (F/T) cycles (−80 °C/+22 °C) or after −80 °C storage for up to 120 days. In...

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Bibliographic Details
Main Authors: Richards, Gary P., Watson, Michael A., Meade, Gloria K., Hovan, Gregory L., Kingsley, David H.
Format: Online
Language:English
Published: Springer-Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505500/